(RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline N-methyltransferase | |||||||
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Identifiers | |||||||
EC number | 2.1.1.115 | ||||||
CAS number | 132084-82-3 | ||||||
Databases | |||||||
IntEnz | IntEnz view | ||||||
BRENDA | BRENDA entry | ||||||
ExPASy | NiceZyme view | ||||||
KEGG | KEGG entry | ||||||
MetaCyc | metabolic pathway | ||||||
PRIAM | profile | ||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||
Gene Ontology | AmiGO / EGO | ||||||
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In enzymology, a (RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline N-methyltransferase (EC 2.1.1.115) is an enzyme that catalyzes the chemical reaction
Thus, the two substrates of this enzyme are S-adenosyl methionine and (RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline, whereas its two products are S-adenosylhomocysteine and N-methyl-(RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline.
This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:(RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline N-methyltransferase. This enzyme is also called norreticuline N-methyltransferase. This enzyme participates in alkaloid biosynthesis i.